Ventriculoperitoneal shunt associated meningitis caused by Globicatella sanguinis: Review of an emerging human pathogen

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Case Report

Author Details : Sharin Varma, Smriti Srivastav, Aparna Ningombam, Deepak Gupta, Purva Mathur*

Volume : 10, Issue : 4, Year : 2024

Article Page : 226-231

https://doi.org/10.18231/j.ijn.2024.046

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Abstract

The genus Globicatella has two species sanguinis and sulfidifaciens. Globicatella sanguinis is an unusual and rare pathogen causing bacteraemia, meningitis, and urinary tract infection in humans. The epidemiology and clinical significance of this pathogen remain largely unkown as Globicatella spp. are rarely isolated from clinical samples. We present a case of 36 year old male who had VP shunt associated meningitis caused by this pathogen. After the extensive literature search till date, we believe that this is the first case of VP shunt associated meningitis in a post trauma patient due to this pathogen. The identification of Globicatella sanguinis was made by Vitek 2 systems and was further confirmed by MALDI-TOF MS. Antibiotic Susceptibility Testing was performed by both Vitek 2 and Kirby bauer disc diffusion method according to CLSI standards for streptococcus spp. Its role as a human pathogen still remains only partially known because of the trouble involved in identification and the small number of reports pertaining to Globicatella. Furthermore, it has been demonstrated that Globicatella spp. are commensal organisms in humans which makes it even more difficult to eatablish it as a cause of disease.
 

Keywords: Globicatella sanguinis, CSF, VP shunt meningitis

How to cite : Varma S, Srivastav S, Ningombam A, Gupta D, Mathur P, Ventriculoperitoneal shunt associated meningitis caused by Globicatella sanguinis: Review of an emerging human pathogen. IP Indian J Neurosci 2024;10(4):226-231

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