Can the high-precision ultrasound—Sonographic system be a predictable diagnostic tool for diagnosing parkinson`s cross-sectional area (CSA) of vagal nerve

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Original Article

Author Details : V Rama Raju*, G Naga Rama Devi

Volume : 10, Issue : 4, Year : 2024

Article Page : 197-203

https://doi.org/10.18231/j.ijn.2024.042

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Abstract

Background: Gut-brain-axis(GBA) is critical in Parkinson disease(PD) progression for which cross-sectional area(CSA) of vagus-nerve/or vagal-nerve (VN, i.e., cranial-nerve X) can be used in the diagnosis of PD. GBA is a bidirectional interaction amid central plus enteric-nervous-system(ENS), connecting sensitive/emotional and cognitive centers of brain via peripheral intestinal functions. GBA interacts with enteric microbiota, central plus enteric nervous systems.
Objective: We hypothesize that the CSA of VN is reduced in PD patients when linked to healthy population group (control participants).
Materials and Methods : The CSA of the VN is measured bidirectionally in >30 Parkinson subjects,>50 healthy controls at the level of common carotid-artery applying higher-dynamic-range ultrasound system (better pixel-resolutions) for high-precision ultrasonography (ultrasonography), confidence of real-time imaging also instant insights with ultrasound solutions.
Results : Mean CSA of left VN in PD and control cohort was 2.10, 1.90, in right 2.54,2.24mm yet no variation within CSA of VN in Parkinson`s when compared to health-population(p?0.079). The mean CSA of right VN was significantly >left (p< 0> Conclusion: The CSA of VN with ultrasonograph system is inconsistent/ or unpredictable diagnostic tool in PD diagnosis.
 

Keywords: Ultrasonography, Pixel­resolutions, Vagal nerve

How to cite : Raju V R, Devi G N R, Can the high-precision ultrasound—Sonographic system be a predictable diagnostic tool for diagnosing parkinson`s cross-sectional area (CSA) of vagal nerve. IP Indian J Neurosci 2024;10(4):197-203

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