Management of motor neuron disease with updated therapies: A review

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Review Article

Author Details : Gautam Kumar, Ravi Kumar*, Kuldeep Saini, Sunita Jha

Volume : 9, Issue : 1, Year : 2023

Article Page : 1-7

https://doi.org/10.18231/j.ijn.2023.001

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Abstract

Motor neuron disorder is a neurodegenerative disorder that causes weakness, respiratory muscle and also bulbar and respiratory failure cause death. Generally motor neuron disorder is sporadic but in some cases roughly 10 is got inherited. According to current studies the new motor neuron disorder genes are found. Pathologically motor neuron disorder & clinically miscellaneous, neuroprotective and remedial targets have been delicate to identified. According to these studies, in motor neuron disorder the evolution growth are similar as bettered understanding of the colorful clinical phenotypes, the boundlessness together the frntotemporal madness, part of genetics, development of standard of care and the global clinical trialspipelines. The vestige of riluzole medicine only disorder modification drug which utilized for the disorder treatment. These drugs have power to improve the cycle of living. In the operation of motor neuron disorder the intensive treatment are important which can be multifunctional. And noninvasive respiratory therapy that involves the delivery of air or a mixture of oxygen combined with other gases by positive pressure into the lungs which can improves the chances of living in MND cases in case of disturbance of exhalation and inhalation. Motor neuron disorder is found further generally in males than females. Motor neuron disease is shown the dropping of neuron in the kidney, spinal cord and mind which show by both up and down motor neuron symptoms & signs they affect arms, bulbar & respiration.
 

Keywords: Motor neuron illness, ALS (Amyotrophic lateral sclerosis), PMA (Progressive muscular atrophy), Respiratory muscles failure & PLS (Primary lateral sclerosis)

How to cite : Kumar G, Kumar R, Saini K, Jha S, Management of motor neuron disease with updated therapies: A review. IP Indian J Neurosci 2023;9(1):1-7

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