Amyloid myopathy: A rare cause of quadreparesis with bulbar palsy

---

Case Report

Author Details : Gaurav Shah*, Jay Chaudhary, Pranav Joshi, Shalin Shah, Mayank Patel, Sudhir Shah

Volume : 8, Issue : 4, Year : 2022

Article Page : 276-278

https://doi.org/10.18231/j.ijn.2022.053

Suggest article by email

Get Permission

---

Abstract

Amyloidosis is a systemic disease that results in the deposition of amyloid fibrils in a variety of tissues causing their progressive dysfunction. Systemic amyloidosis involves Kidney, Heart, Skin, Peripheral nerve and rarely muscle. Amyloid myopathy (AM) is a rare manifestation of primary systemic amyloidosis (AL). Amyloid myopathy frequently occurs in the setting of systemic amyloidosis and less commonly in isolation (isolated amyloid myopathy). It can present with proximal muscle weakness and an increased creatinine kinase level. Muscle involvement is associated with amyloid deposits around small blood vessels and muscle fibers. We present a case of rapidly progressive muscle weakness with dysphagia. The diagnosis was confirmed by demonstration of amyloid protein by Thioflavin immune-florescence staining on abdominal fat pad biopsy.
 

Keywords: Amyloidosis, Myopathy, Quadreparesis

How to cite : Shah G, Chaudhary J, Joshi P, Shah S, Patel M, Shah S, Amyloid myopathy: A rare cause of quadreparesis with bulbar palsy. IP Indian J Neurosci 2022;8(4):276-278

This is an Open Access (OA) journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.