Role of Serum CPK and Serum Magnesium Level as a Predictor of Impending Intermediate Syndrome in Patients of OP Poisoning

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Original Article

Author Details : Singla Rahul, Singh Veer B., Meena Babu L., Kumar Harish, Kumar Deepak, Sidana Shivani, Chandra Subh

Volume : 2, Issue : 1, Year : 2016

Article Page : 22-25

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Abstract

Introduction: Organophosphorus poisoning is one of the most common and deadliest poisoning especially in country like India. The intermediate syndrome occurred after the acute cholinergic syndrome but before organophosphate-induced delayed Polyneuropathy is characterised by the weakness of the muscles of respiration and of proximal limb muscles. Early identification can reduce morbidity and mortality.
Aim: To assess importance of serum CPK and serum Magnesium level in patients of OP poisoning as marker OP intermediate syndrome.
Material method: This was cross sectional study in PBM hospital over 93 patients over a period of 1 year. Serum CPK and magnesium level were assessed on admission and day 5 and were compared in patients who developed and didn’t intermediate syndrome.
Result: Thus, CPK level on day 1 as well as day 5 but not magnesium can be used as a predictor for the intermediate syndrome.

Key words: CPK (creatinine Pospho-kinase), Intermediate syndrome, Magnesium, Organophosphorus poisoning

How to cite : Rahul S, Singh Veer B., Meena Babu L., Harish K, Deepak K, Shivani S, Subh C, Role of Serum CPK and Serum Magnesium Level as a Predictor of Impending Intermediate Syndrome in Patients of OP Poisoning. IP Indian J Neurosci 2016;2(1):22-25

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