Guillain-barré syndrome after purified vero cell rabies vaccination: An unusual case report

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Case Report

Author Details : Khichar Shubhakaran*, Amita Bhargava, Sanjay Khoont

Volume : 7, Issue : 2, Year : 2021

Article Page : 175-177

https://doi.org/10.18231/j.ijn.2021.029

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Abstract

Guillain-Barré syndrome (GBS) can be described as a collection of clinical syndromes that manifests as an acute inflammatory polyradiculoneuropathy with resultant weakness and diminished reflexes. Regarding pathophysiology of GBS, it is believed that autoimmunity- molecular mimicry plays a role in its pathogenesis. As the vaccines have an effect on the immune system it is reasonable that immunizations may be associated with subsequent GBS. Although rabies vaccines containing neural elements are very well known cause for GBS, no such positive correlation has been proven after newer formulations of rabies vaccine, derived from chick embryo cells. Here we report a case of GBS which developed after 5 weeks of anti-rabies vaccination (Purified Vero cell rabies vaccine) which was given after dog bite.
 

Keywords: Guillain Barre Syndrome, Antirabies vaccine, Purified Vero cell rabies vaccine

How to cite : Shubhakaran K, Bhargava A, Khoont S, Guillain-barré syndrome after purified vero cell rabies vaccination: An unusual case report. IP Indian J Neurosci 2021;7(2):175-177

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