Neuro vascular injury profile in CVA patients: A study on correlation between hematological indices and severity score in acute ischemic stroke

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Original Article

Author Details : Sailaja Y, V Ramakrishnan, Naveen P, C Mutharasu*

Volume : 6, Issue : 2, Year : 2020

Article Page : 111-115

https://doi.org/10.18231/j.ijn.2020.023

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Abstract

Acute ischemic stroke results from sudden loss of blood circulation to an area of cerebral hemispheres leading to irreversible brain injury and neurological deficits persisting for more than 24 hours or until death. It accounts for 80-87% of all strokes. In this study, we aim to find the association between various hematological indices such as Mean platelet Volume (MPV), Platelet  distributionWidth (PDW), Neutrophil to Lymphocyte Ratio (NLR), Platelet to Lymphocyte ratio (PLR) and National Institute of Health Stroke Scale (NIHSS).
Materials and Methods: It was a prospective study done at Department of Neurology at Meenakshi Medical College Hospital and Research Institute, Kancheepuram, Tamil Nadu in which 100 patients of Acute Ischemic stroke were divided into two groups basing on NIHSS score. Proper Exclusion criteria were carried out and the patients’ blood samples were taken. Various Hematological indices were measured and statistical analysis was done using SPSS Software.
Results: There is positive correlation between NLR, PLR and NIHSS score. It is statistically significant association. But there is no statistical significance between Platelet indices and NIHSS score.
Conclusion: Being Low cost and easy to measure nature of NLR and PLR, these indices can be used in the prediction of the prognosis in the Acute Ischemic Stroke patients.

Keywords: Mean platelet Volume (MPV), Platelet distribution Width (PDW), Neutrophil to Lymphocyte Ratio (NLR), Platelet to Lymphocyte ratio (PLR), National Institute of Health Stroke, Scale (NIHSS).

How to cite : Sailaja Y, Ramakrishnan V, Naveen P, Mutharasu C , Neuro vascular injury profile in CVA patients: A study on correlation between hematological indices and severity score in acute ischemic stroke. IP Indian J Neurosci 2020;6(2):111-115

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