A preterm female neonate was born to a 20-year-old primiparous woman with a history of second degree consanguineous marriage, septic abortion, PCOS and hypothyroidism at 34 weeks of gestation. Prenatal screenings were negative for trisomies and major genetic abnormalities. Postnatal neuro imaging revealed agenesis of the corpus callosum (ACC), a rare congenital malformation. Despite the absence of advanced maternal age. The neonate required neonatal intensive care unit (NICU) support and was placed on continuous positive airway pressure (CPAP) for respiratory assistance. During NICU management, the neonate displayed poor heart and respiratory function and a multidisciplinary care approach was implemented. This case highlights the significance of thorough prenatal and postnatal monitoring in consanguineous pregnancies, even in young mothers with atypical maternal histories, and emphasises the need for specialised care in such cases.
Keywords: Preterm Infant, Agenesis of corpus callosum, Consanguinity, Congenital malformations, Prenatal screening, Postnatal neuroimaging, Maternal hypothyroidism
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How to Cite This Article
Vancouver
Ahmed AM, Gaunker SN. Agenesis of corpus callosum in a preterm neonate [Internet]. IP Indian J Neurosci. 2025 [cited 2025 Oct 02];11(2):105-108. Available from: https://doi.org/10.18231/j.ijn.2025.022
APA
Ahmed, A. M., Gaunker, S. N. (2025). Agenesis of corpus callosum in a preterm neonate. IP Indian J Neurosci, 11(2), 105-108. https://doi.org/10.18231/j.ijn.2025.022
MLA
Ahmed, Amir Minhaj, Gaunker, Shrisha Naik. "Agenesis of corpus callosum in a preterm neonate." IP Indian J Neurosci, vol. 11, no. 2, 2025, pp. 105-108. https://doi.org/10.18231/j.ijn.2025.022
Chicago
Ahmed, A. M., Gaunker, S. N.. "Agenesis of corpus callosum in a preterm neonate." IP Indian J Neurosci 11, no. 2 (2025): 105-108. https://doi.org/10.18231/j.ijn.2025.022